Nikoloz Sanishvili
- Birthday: 12/24/1902
- Deathday: 10/26/1996
- Place of birth: Kutais, Kutaisi Governorate, Russian Empire [now Kutaisi, Republic of Georgia]
- Fame for: Directing
- Also known as: Николоз Санишвили, Николай Санишвили, Николоз Константинович Санишвили, Nikoloz Sanov